Evangelos J Giamarellos-Bourboulis Selected Research

Pyelonephritis

1/2022	Meropenem-vaborbactam: a critical positioning for the management of infections by Carbapenem-resistant Enterobacteriaceae.
1/2020	Staphylococcus Aureus Osteomyelitis as an Inducer of Tolerance to Escherichia Coli Pyelonephritis: an Experimental Study.
12/2018	Effect and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial.
1/2018	Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial.
5/2016	Reverse kinetics of angiopoietin-2 and endotoxins in acute pyelonephritis: Implications for anti-inflammatory treatment?
9/2015	Esmolol: immunomodulator in pyelonephritis by Pseudomonas aeruginosa.
8/2014	Immunomodulatory intervention with interferon-γ in Escherichia coli pyelonephritis.
1/2010	Macrocycle molecules for the management of systemic infections: the clarithromycin paradigm.
1/2010	Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection.
5/2006	Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae.

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Evangelos J Giamarellos-Bourboulis Research Topics

Disease

98	Sepsis (Septicemia) 03/2022 - 09/2002
66	Infections 03/2022 - 03/2002
29	COVID-19 04/2022 - 01/2020
25	Necrosis 12/2021 - 10/2004
22	Septic Shock (Toxic Shock Syndrome) 11/2021 - 09/2002
21	Inflammation (Inflammations) 01/2022 - 05/2002
19	Critical Illness (Critically Ill) 04/2022 - 09/2002
17	Ventilator-Associated Pneumonia 01/2022 - 01/2008
17	Pneumonia (Pneumonitis) 10/2021 - 11/2008
15	Hidradenitis Suppurativa 11/2021 - 06/2010
13	Pyelonephritis 01/2022 - 01/2004
11	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2021 - 09/2002
10	Shock 04/2014 - 10/2006
9	Multiple Organ Failure (MODS) 01/2022 - 09/2002
7	Wounds and Injuries (Trauma) 01/2022 - 05/2005
7	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 01/2020
6	Coinfection 03/2022 - 12/2020
6	Lymphopenia (Lymphocytopenia) 10/2021 - 12/2010
5	Communicable Diseases (Infectious Diseases) 09/2021 - 10/2012
5	Pancreatitis 01/2021 - 05/2002
5	Osteomyelitis 01/2020 - 07/2008
5	Multiple Trauma (Multiple Injuries) 01/2020 - 05/2005
5	Bacterial Infections (Bacterial Infection) 01/2020 - 01/2011
4	Urinary Tract Infections (Urinary Tract Infection) 01/2022 - 12/2015
4	Intraabdominal Infections 01/2022 - 01/2010
4	Neoplasms (Cancer) 12/2019 - 05/2004
4	Fever (Fevers) 01/2019 - 01/2008
4	Peritonitis 06/2013 - 03/2003
4	Hemorrhagic Shock 01/2011 - 10/2006
3	Disease Progression 01/2022 - 01/2010
3	Human Influenza (Influenza) 01/2021 - 03/2012
3	Ulcerative Colitis 06/2019 - 06/2006
3	Crohn Disease (Crohn's Disease) 06/2019 - 06/2006
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/2019 - 06/2006
3	Bacteremia 12/2018 - 01/2017
3	Acute Kidney Injury (Acute Renal Failure) 11/2017 - 09/2002

Drug/Important Bio-Agent (IBA)

27	CytokinesIBA 04/2022 - 10/2006
24	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2020 - 08/2003
23	Biomarkers (Surrogate Marker)IBA 03/2022 - 04/2011
21	Interleukin-6 (Interleukin 6)IBA 01/2022 - 08/2003
19	Clarithromycin (Biaxin)FDA LinkGeneric 01/2022 - 01/2004
17	InterleukinsIBA 12/2021 - 09/2006
13	Anti-Bacterial Agents (Antibiotics)IBA 03/2022 - 06/2009
12	ProcalcitoninIBA 03/2022 - 09/2002
12	EndotoxinsIBA 11/2021 - 01/2003
10	Interleukin-10 (Interleukin 10)IBA 10/2021 - 02/2006
10	Angiopoietin-2IBA 10/2021 - 11/2008
9	C-Reactive ProteinIBA 01/2022 - 10/2009
9	Triggering Receptor Expressed on Myeloid Cells-1IBA 10/2021 - 01/2006
8	Urokinase Plasminogen Activator ReceptorsIBA 01/2022 - 11/2011
8	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2022 - 01/2016
8	MacrolidesIBA 12/2021 - 01/2008
8	Immunologic Factors (Immunomodulators)IBA 11/2021 - 02/2005
8	Interleukin-8 (Interleukin 8)IBA 01/2017 - 01/2006
8	Malondialdehyde (Propanedial)IBA 07/2013 - 01/2004
7	Adalimumab (Humira)FDA Link 11/2021 - 08/2016
7	Colistin (Coly-Mycin)FDA Link 09/2021 - 11/2002
7	salicylhydroxamic acid (SHAM)IBA 01/2020 - 07/2008
7	LipopolysaccharidesIBA 01/2017 - 04/2011
6	InterferonsIBA 04/2022 - 12/2009
6	Interferon-gamma (Interferon, gamma)IBA 12/2021 - 12/2008
6	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 12/2007
6	EnzymesIBA 02/2018 - 01/2007
6	Moxifloxacin (Avelox)FDA Link 08/2017 - 06/2008
6	Amikacin (A.M.K)FDA LinkGeneric 09/2015 - 02/2004
5	HLA-DR Antigens (HLA-DR)IBA 01/2022 - 01/2010
5	Antigen-Antibody Complex (Immune Complex)IBA 01/2022 - 02/2015
5	CreatinineIBA 01/2022 - 07/2008
5	Immunoglobulin M (IgM)IBA 01/2021 - 09/2012
5	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021 - 01/2010
4	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 10/2021 - 01/2020
4	Pharmaceutical PreparationsIBA 04/2021 - 01/2018
4	Ferritins (Ferritin)IBA 01/2021 - 01/2019
4	RNA (Ribonucleic Acid)IBA 01/2021 - 06/2009
4	DNA (Deoxyribonucleic Acid)IBA 02/2018 - 03/2012
4	InflammasomesIBA 01/2017 - 11/2010
4	Interleukin-17 (Interleukin 17)IBA 10/2016 - 08/2013
4	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 08/2010 - 05/2004
3	Immunomodulating AgentsIBA 01/2022 - 01/2021
3	Biological ProductsIBA 01/2022 - 07/2017
3	Interleukin-1 (Interleukin 1)IBA 01/2022 - 01/2011
3	Carbapenems (Carbapenem Antibiotics)IBA 01/2022 - 01/2018
3	meropenem and vaborbactamIBA 01/2022 - 01/2018
3	Dexamethasone (Maxidex)FDA LinkGeneric 10/2021 - 01/2013
3	Azithromycin (Zithromax)FDA LinkGeneric 09/2021 - 08/2014
3	VaccinesIBA 04/2021 - 01/2020
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 01/2010
3	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2021 - 11/2020
3	Interleukin-18 (Interleukin 18)IBA 01/2021 - 12/2009
3	Rifampin (Rifampicin)FDA LinkGeneric 01/2021 - 01/2007
3	Proteins (Proteins, Gene)FDA Link 06/2019 - 01/2016

Therapy/Procedure

24	Therapeutics 11/2021 - 03/2002
7	Immunotherapy 01/2022 - 05/2011
6	Artificial Respiration (Mechanical Ventilation) 04/2022 - 04/2008
6	Ligation 05/2016 - 08/2003
5	Immunomodulation 11/2021 - 11/2008
5	Resuscitation 01/2011 - 10/2006
4	Intravenous Administration 11/2008 - 03/2003
3	Critical Care (Surgical Intensive Care) 01/2022 - 09/2004
3	Catheters 12/2020 - 01/2004